Online Management of Breast Diseases Patient Education |  Physician Guidelines |  Treatment Index
News |  TransMed |  E-Mail |  Disclaimer

Onc.Protocol:TAXOL

 

 

ONCOLOGIC PROTOCOL

TAXOL - STAGE IV

MAJOR INDICATIONS: TREATMENTS FOR STAGE IV BREAST CANCER
IDENTIFICATION: Paclitaxel (Taxol)
This drug has been approved by the FDA (Food and Drug Administration) for the treatment of breast cancer.
Doses: 175 mg./M2
Route: Given intravenously (IV) for 3 hours
Duration and timing: Given once every 3 weeks
Treatments are generally continued as long as the drug keeps the breast cancer from growing unless there are unacceptable side effects.
Possible Side effects:
  • Hematopoetic: decrease in blood cells, especially white cells (neutropenia) but also red cells (anemia) and or platelets (thrombocytopenia)
  • Gastrointestinal: mild to moderate nausea and vomiting (which may be decreased or prevented with medications); diarrhea; mouth sores; decreased appetite; abnormalities in liver function tests; inflammation of the pancreas (pancreatitis); taste changes
  • Integmentary: hair loss (usually complete); changes in nails
  • Fertility: effect on fertility is unknown; this drug should not be taken by women who are pregnant or breast feeding
  • Cardiovascular: chest pain; increase in blood pressure (hypertension); low blood pressure (hypotension); slowing of the heart beat (bradycardia); serious heart problems are rare (1.5%) in patients who do not have a history of heart problems; irritation to the vein where the drug is given (phlebitis)
  • Neurological: numbness, tingling and/or burning sensations in hands and/or feet (peripheral neuropathy); weakness in the hands and/or feet
  • Allergic (hypersensitivity reactions): flushing, rash, chest pain or heaviness, back pain, shortness of breath, wheezing, fever, shaking, chills, low blood counts.

IT IS IMPORTANT THAT PATIENTS RECEIVE MEDICINES TO PREVENT HYPERSENSITIVITY REACTIONS BEFORE EACH DOSE OF PACLITAXEL

  • Other: fatigue; muscle aches (myalgia) and joint pain (arthralgia)

Back gif

 

1997 - TransMed Network