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MALE BREAST CANCER

 

BREAST CANCER IN MALE PATIENTS (SUMMARY)

EPIDEMIOLOGICAL STATISTICS
 
BREAST CANCER MALE PATIENTS FEMALE PATIENTS
CASES PER YEAR IN US 1000 182000
   
CLINICAL PRESENTATION
 
-Unilateral, Hard, Breast Mass
-Bloody Nipple Discharge
-Pain and or Tenderness
-Mean age at presentation: 59 Years
   
SPECIFIC RISK FACTORS FOR MALE PATIENTS
 
-Cirrhosis
-Liver diseases
-Gynecomastia
-Klinefelter's Syndrome
-Hyper-estrogenism
   
IMAGING AND DIAGNOSTIC STUDIES
 
-Mammography (Essential)
- FNA and Core Biopsy
   
HISTOLOGICAL TYPES
 
-Invasive Ductal Carcinoma - Most Frequent
-Invasive Lobular Carcinoma - Extremely Rare
-All Cell types can be found
   
STANDARD TREATMENT FOR LOCALLY INVASIVE CARCINOMA
 
-Surgical / Local: Same guidelines used for female patients
-Systemic: Same guidelines used for female patients
-Hormonal: Debatable / Same guidelines used for female patients
   
STANDARD TREATMENT FOR DISTANT METASTASIS
 
-Initial Approach: Orchiectomy versus Tamoxifen
-Secondary Approach: Systemic Chemotherapy if no response to hormonal manipulation
   
PROGNOSIS
 
OVERALL SURVIVAL
STAGE I 90 % at 10 YEARS
Less than 2 cm 53 % at 5 YEARS
2 to 5 cm 44 % at 5 YEARS
More 5 cm 25 % at 5 YEARS
From Initial Appearance of Distant Metastasis 26.5 months Average Survival

References:

  • Patel HZ et al.: Male breast cancer. 1989;64:1583
  • Demeter JG et al: Breast cancer in the male patient. Cancer 1990;65:2342

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