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Onc.Protocol:ARIMIDEX

 

 

ONCOLOGIC PROTOCOL

ANASTROZOLE (ARIMIDEX)

MAJOR INDICATIONS: HORMONAL TREATMENTS FOR BREAST CANCER (ALL STAGES)
IDENTIFICATION: Anastrazole (Arimidex)
This drug has been approved by the FDA (Food and Drug Administration) for the treatment of metastatic (Stage IV) breast cancer.
Dose: 5 mg (1 tablet) per day.
Route: Given orally
Duration and timing: In the treatment of stage IV disease treatment is continued until disease progression.
Possible Side effects:
  • Gastrointestinal: possible nausea and vomiting (which may be decreased or prevented with medications), abdominal pain, constipation, diarrhea, loss of appetite.
  • Systemic: menopausal symptoms (hot flashes, night sweats, menstrual irregularity), bone or tumor pain.
  • Fertility: adverse effect on fertility is known; this drug should not be taken by women who are pregnant or breast feeding.
  • Respiratory: instances of pulmonary embolism have occurred (blood clot going to the lung), dyspnea (feeling of shortness of breath), cough and pharyngitis.
  • Other: increased risk of developing blood clots, edema, dizziness, headaches, depression, rash and generalized weakness have all been encountered.

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